Endocrine Abstracts

Cardioprotective actions of urocortin (Ucn) I have been proposed by several studies and may play a critical role on stress adaptation. And one of the beneficial actions on cardiovascular cells may be anti-oxidative actions. In addition, Ucn I may be regulated by oxidative stress, therefore, the present study is designed to reveal anti-oxidative actions of Ucns on cardiomyocytes. Mouse atrial cell line, HL-1 cardiomyocytes, was cultured in standard Claycomb medium supplemented ...

Seventy six-year-old man was referred to our hospital for examination of hypertension and hypokalemia. His blood pressure was uncontrolled although he was taking amlodipine besilate, spironolacton and candesartan. In addition, he suffered from atrial fibrillation and chronic heart failure. His serum potassium was low (2.8 mmol/l) and bilateral adrenal glands were found swelling. Hence, we investigated him thoroughly on the suspicion for primary aldosteronism.<p class="abst...